Animal tests have revealed that extremely high doses of cannabinoids are needed to have lethal effect. This has led scientists to conclude that the ratio of the amount of cannabinoids necessary to get a person intoxicated (i.e., stoned) relative to the amount necessary to kill them is 1 to 40,000. In other words, to overdose, you would have to consume 40,000 times as much marijuana as you needed to get stoned. In contrast, the ratio for alcohol varies between 1 to 4 and 1 to 10. It is easy to see how upwards of 5000 people die from alcohol overdoses every year and no one EVER dies of marijuana overdoses.